Antibodies under a microscope

Ab04185-10.3

LY2062430 (Solanezumab, hu266)

Description

Recombinant monoclonal antibody to Amyloid beta A4 protein. Manufactured using AbAbТs Recombinant Platform with variable regions (i.e. specificity) from the synthetic antibody LY2062430 (Solanezumab, hu266). This is a reformatted human IgG1 Fc SilentЩ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Target

Amyloid beta A4 protein

Target Alias Names

APP, A? peptide, Abeta, A-beta, A?, A?42, amyloid beta peptide, Alzheimer disease amyloid protein, Beta-amyloid precursor protein, Protease nexin-II, humanized m266.2

Isotype/Mimetic

IgG1

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression