Enables DNA binding activity, histone deacetylase binding activity, and protein homodimerization activity. Involved in several processes, including alternative mRNA splicing, via spliceosome, positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway, and regulation of transcription by RNA polymerase II. Acts upstream of or within double-strand break repair via homologous recombination. Located in chromatin, nuclear matrix, and paraspeckles. [provided by Alliance of Genome Resources, Jul 2025]
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