Enables 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including early endosome to late endosome transport, macroautophagy, and phosphatidylinositol-3-phosphate biosynthetic process. Acts upstream of or within autophagy and positive regulation of protein lipidation. Located in autolysosome, late endosome, and midbody. Part of phosphatidylinositol 3-kinase complex, class III. [provided by Alliance of Genome Resources, Jul 2025]
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