Description
NFkB-p105 a transcription factor of the nuclear factor-kappaB ( NFkB) group. Undergoes cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of NFkB. NFkB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products.
Target
NFKB1
Target Alias Names
NF-kappa-B1, p84/NF-kappa-B1 p98, NFKB1, DNA-binding factor KBF1, EBP-1, NFkB-p50
Isotype/Mimetic
Rabbit IgG
Animal-Derived Biomaterials Used
None
Sequence Available
Yes
Original Discovery Method
Unknown
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Unknown discovery source/method, In vitro recombinant expression