Description
Growth differentiation factor-15 (GDF-15) is a stress responsive cytokine. It is highly expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells, and vascular smooth muscle cells in normal and pathological condition. GDF-15 increases during tissue injury and inflammatory states and is associated with cardiometabolic risk.
Target
GDF-15
Isotype/Mimetic
human IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
Yes
Original Discovery Method
Unknown
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), Unknown discovery source/method, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation