Description
This product is a mutant humanized monoclonal antibody against human VEGF. Mab Y0317 has strong binding affinities for VEGF, inhibit VEGF-induced proliferation of endothelial cells in vitro, inhibit VEGF-induced angiogenesis in vivo, and inhibit tumor growth in vivo. It may play a role in preventing tumor.
Target
VEGFA
Target Alias Names
Vascular Endothelial Growth Factor A, Vascular Permeability Factor, VEGF, VPF, Vascular Endothelial Growth Factor A121, Vascular Endothelial Growth Factor A165, Vascular Endothelial Growth Factor, VEGF-A, MVCD1, Y0317
Isotypes/Mimetics
Humanized IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression