Description
This product is a humanized antibody targeting human vascular endothelial growth factor (VEGF). Compared with bevacizumab, 8B13 has a higher affinity to VEGF, significantly more strongly suppressed HUVEC proliferation ability and anti-tumor activity in vivo.
Target
VEGFA
Target Alias Names
VEGFA, VEGF, Vascular Endothelial Growth Factor, VPF, VEGF-A, Vascular Endothelial Growth Factor A, MVCD1, Vascular Permeability Factor
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression