Description
Recombinant monoclonal antibody to TYRP1. Clone 20D7S is a IgG1 that has increased activity in the treatment of disorders characterized by KIR3DL2- expressing cells, particularly CD4+ T cells, including malignancies such as Mycosis Fungoides and Sezary Syndrome.
Target
TYRP1
Target Alias Names
TRP, CAS2, CATB, GP75, OCA3, TRP1, TYRP, b-PROTEIN
Isotypes/Mimetics
Human IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression