Description
This is a humanized antibody derived from murine antibody 5E10, which specifically binds the LIGHT polypeptide. Antibody h5E10 can be used in the treatment or diagnosis of immune, inflammatory and malignant diseases or conditions.
Target
TNFSF14
Target Alias Names
TNF Superfamily Member 14, Tumor Necrosis Factor (Ligand) Superfamily, Member 14, Herpesvirus Entry Mediator Ligand, HVEML, LIGHT, Tumor Necrosis Factor Ligand Superfamily Member 14, Tumor Necrosis Factor Superfamily Member 14
Isotypes/Mimetics
Humanized IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression