Description
Provided is an antibody capable of specific binding and capable of activating human death receptor 5 (DR5), and belongs to a full-humanized antibody. The antibody is obtained by performing quintuple screening in a high-capacity full-humanized phage antibody library by using human death receptor DR5 extracellular protein as a target antigen.
Target
TNFRSF10B
Target Alias Names
TNF Receptor Superfamily Member 10b, Tumor Necrosis Factor Receptor Superfamily, Member 10b, TNF-Related Apoptosis-Inducing Ligand Receptor 2, Death Receptor 5, TRAIL-R2, TRAILR2, KILLER, TRICK2, ZTNFR9, DR5, P53-Regulated DNA Damage-Inducible Cell Death Receptor(Killer), Tumor Necrosis Factor Receptor Superfamily Member 10B, Tumor Necrosis Factor Receptor-Like Protein ZTNFR9
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression