Description
Provided is an antibody against human transforming growth factor beta receptor II (TGFβRII). The anti-human TGFβRII mAb TGF2 exhibit a high affinity, with KD values of 78 pM. TGF2 exhibits intermediate or minimal cross reactivity with mouse TGFβRII. However, mAbs TGF2 do not block human TGFβ 1 binding to mouse TGFβRTI.
Target
TGFBR2
Target Alias Names
Transforming Growth Factor Beta Receptor 2, Transforming Growth Factor, Beta Receptor II (70/80kDa), Transforming Growth Factor Beta Receptor II, TGF-Beta Type II Receptor, EC 2.7.11.30, TbetaR-II, TGFR-2, Transforming Growth Factor, Beta Receptor II Epsilon, Transforming Growth Factor, Beta Receptor II Alpha, Transforming Growth Factor, Beta Receptor II Delta, Transforming Growth Factor, Beta Receptor II Gamma, Transforming Growth Factor Beta Receptor Type IIC, Transforming Growth Factor, Beta Receptor II Beta, Transforming Growth Factor-Beta Receptor Type II, TGF-Beta Receptor Type IIB
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression