Description
Provided is a protease-regulated antibody which specifically binds to tissue factor pathway inhibitor (TFPI). The antibodies are useful for the treatment of bleeding disorders, such as hemophilia.
Target
TFPI
Target Alias Names
Tissue Factor Pathway Inhibitor, Extrinsic Pathway Inhibitor, Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor), TFPI1, LACI, EPI, Lipoprotein-Associated Coagulation Inhibitor, Anti-Convertin, TFI
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression