Description
This product is a recombinant chimeric (mouse/human) antibody that recognizes (both natural and recombinant) human TACSTD2 (Extracellular domain, aa 34 to 72). It binds to the extracellular region of human Trop-2 with high affinity and exhibits high ADCC activity and high antitumor activity.
Target
TACSTD2
Target Alias Names
EGP1, GP50, M1S1, EGP-1, TROP2, GA7331, GA733-1, tumor-associated calcium signal transducer 2, 40kD glycoprotein, identified by monoclonal antibody GA733, cell surface glycoprotein TROP2, cell surface glycoprotein Trop-2, epithelial glycoprotein-1, gastrointestinal tumor-associated antigen GA7331, membrane component, chromosome 1, surface marker 1, pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331, trophoblast cell surface antigen 2, truncated TACSTD2
Isotypes/Mimetics
Chimeric (mouse/human) IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression