Description
This is a monoclonal antibody which specifically binds to sclerostin. The antibody 2 can be used for treating Chronic kidney disease (CKD) with evidence of Mineral and Bone Disorder (MBD) by antagonizing Sclerostin expression, secretion, signaling and function.
Target
SOST
Target Alias Names
Sclerostin, Sclerosteosis, DAND6, SOST1, VBCH, CDD
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression