Description
An isolated human antibody 42C1 that specifically binds to SLPI with high affinity. The antibody modulates and neutralizes the activity of SLPI. SLPI is a highly cationic single-chain protein with eight intramolecular disulfide bonds.
Target
SLPI
Target Alias Names
SLPI, secretory leukocyte peptidase inhibitor, ALP, MPI, ALK1, BLPI, HUSI, WAP4, WFDC4, HUSI-I, antileukoproteinase, HUSI-1, protease inhibitor WAP4, mucus proteinase inhibitor, seminal proteinase inhibitor, WAP four-disulfide core domain protein 4, secretory leukocyte protease inhibitor (antileukoproteinase)
Isotype/Mimetic
Human IgG2
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression