Description
Provided are monoclonal antibodies that bind to, and inhibit the activity of human FPN1, and which are effective in maintaining or increasing the transport of iron out of mammalian cells and/or maintaining or increasing the level of serum iron, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a subject in vivo.
Target
SLC40A1
Target Alias Names
Solute Carrier Family 40 Member 1, Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 3, Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1, SLC11A3, IREG1, FPN1, Iron-Regulated Transporter 1, Iron Regulated Gene 1
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression