Description
Provided is an antibody h24A3-H2e/L1 which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation. The binding activity of the antibody to the mouse Siglec-15 protein was evaluated, 6.9 pM.
Target
SIGLEC15
Target Alias Names
Sialic Acid Binding Ig Like Lectin 15, CD33 Antigen-Like 3, CD33 Molecule-Like 3, SIGLEC-15, CD33L3, Sialic Acid Binding Ig-Like Lectin 15, Sialic Acid-Binding Ig-Like Lectin 15, HsT1361
Isotype/Mimetic
Humanized (rat/human) IgG2
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression