Description
This is a fully human monoclonal antibody (clone 6D7OP) against human sonic hedgehog homolog (Shh). The antibody 6D7OP also binds to human and mouse Indian hedgehog (Ihh) in both the ELISA and Biacore formats. It also neutralizes Ihh Activity in the C3H10T1/2 Cell Osteogenesis. 6D7OP is useful in the treatment studies of diseases associated with the activity and overproduction of Shh and as diagnostics.
Target
SHH
Target Alias Names
Sonic Hedgehog, Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains, ShhNC, Sonic Hedgehog (Drosophila) Homolog, Sonic Hedgehog Homolog (Drosophila), Sonic Hedgehog Homolog, Sonic Hedgehog Protein, MCOPCB5
Isotype/Mimetic
Human IgG1
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression