Description
This product is a recombinant human antibody that recognizes SCARB1. The antibody binds to a SR-BI target region involved in HCV E2 binding. scFVC11 can block HCV infection of cultured human hepatocytes.
Target
SCARB1
Target Alias Names
Scavenger Receptor Class B Member 1, CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor)-Like 1, CD36 And LIMPII Analogous 1, CD36L1, CLA-1, SR-BI, CLA1, SRB1
Isotypes/Mimetics
Human IgG4, λ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression