Description
The recombinant human antibody binds to Repulsive Guidance Molecule a (RGMa). The antibody cross reacts with human, cynomolgus and rat RGMa protein. The KD value for hRGMa, cyno RGMa and rat RGMa is 7.3 nM, 8.8 nM and 19 nM, respectively. The epitope for this antibody is located in the N-terminal region of RGMa.
Target
RGMA
Target Alias Name
RGM
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression