Description
Monoclonal antibody to PLA2 is a fully human antibody that can be potentially used in the treatment of Atherosclerosis and restenosis. This antibody can inhibit PLA2 function at IC50 <, 2 nM. The epitope recognized by the monoclonal antibody to PLA2 is mapped to amino acid residues (PQFL).
Target
PLA2
Target Alias Names
PLA2, Phospholipase A2, PLA2G1B, PLA2G2A, PLA2G2C, PLA2G2D, PLA2G2E, PLA2G2F
Isotypes/Mimetics
Human IgG4, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression