Description
Provided is a monoclonal antibody for a proprotein convertase subtilisin Kexin 9 (PCSK9). The monoclonal antibody can block the binding of PCSK9 to a LDL receptor so that the level of LDL-C is reduced. The monoclonal antibody provides a very effective agent for treating various CVD diseases.
Target
PCSK9
Target Alias Names
Proprotein Convertase Subtilisin/Kexin Type 9, Subtilisin/Kexin-Like Protease PC9, NARC-1, NARC1, PC9, Convertase Subtilisin/Kexin Type 9 Preproprotein, Hypercholesterolemia, Autosomal Dominant 3, Neural Apoptosis Regulated Convertase 1, Neural Apoptosis-Regulated Convertase 1
Isotypes/Mimetics
Human IgG4, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression