Description
Recombinant Human Antibody (mab 911) is capable of binding to NGF, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-NGF mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-NGF mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
NGF
Target Alias Names
NGF, nerve growth factor (beta polypeptide), NGFB, HSAN5, Beta-NGF, beta-nerve growth factor, nerve growth factor, beta subunit
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression