Description
This product is a recombinant humanized version of the OGD1.0.0 antibody that recognizes MSTN. The humanized anti-GDF-8 antibody VH region constructed using DP47 and JH3 is called VH1, whereas the humanized anti-GDF-8 antibody VL region constructed using DPK9 and JK1 is called VL1. A humanized anti-GDF-8 antibody comprising VH1 and VL1 is called OGD1.1.1. It retains the capacity to specifically bind GDF-8 with high affinity and to neutralize GDF-8 activity.
Target
MSTN
Target Alias Names
Myostatin, GDF8, Growth Differentiation Factor 8, Growth/Differentiation Factor 8, MSLHP, GDF-8
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression