Description
This product is a recombinant human antibody that recognizes MSTN. It specifically binds to Growth and Differentiation Factor-8 (GDF8) and blocks GDF8 activity. This antibody exhibits strong binding to GDF8 but no binding to GDF11. It can produce significant increases in muscle mass when administered to mice over a range of doses.
Target
MSTN
Target Alias Names
MSTN, myostatin, GDF8, MSLHP, growth/differentiation factor 8, GDF-8, growth differentiation factor 8
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression