Description
The recombinant antibody MF-A is specific for the membrane-anchored, 40 kDa mesothelin polypeptide, which is overexpressed in several tumors. It was used for the cell-based affinity determination, determined by fluorescence-activated cell sorting (FACS) combined with Scatchard analysis, and live cell enzyme-linked immunosorbed assay (ELISA).
Target
MSLN
Target Alias Names
Mesothelin, Pre-Pro-Megakaryocyte-Potentiating Factor, CAK1 Antigen, MPF, Soluble MPF Mesothelin Related Protein, Megakaryocyte Potentiating Factor, SMRP
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression