Description
Provided is a monoclonal antibody BVh3/CVI3 that binds to myelin associated glycoprotein (MAG). BVh3/CVI3 promotes oligodendrocyte survival in a human suffering or at risk of developing stroke or another neurological disease.
Target
MAG
Target Alias Names
Myelin Associated Glycoprotein, Sialic Acid Binding Ig-Like Lectin 4A, SIGLEC-4A, GMA, Sialic Acid-Binding Immunoglobulin-Like Lectin 4A, Myelin-Associated Glycoprotein, SIGLEC4A, S-MAG, SPG75
Isotype/Mimetic
Humanized (mouse/human) IgG1
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression