Description
The recombinant human monoclonal antibody specifically binds to LDL. It is able to bind to MDA-LDL, intact OxLDL, OxLDL lipid and protein moieties but not to those of native LDL. This anti-LDL antibody IK17 can block the uptake of OxLDL by macrophages.
Target
LDL
Target Alias Names
Low-density lipoprotein, LDL, Ldl cholesterol
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression