Description
This is a chimeric antibody derived from murine antibody 1H12, which binds to the LG4-5 domain of chain α3 of human protein laminin-5. Monoclonal antibody ch1H12 inhibits the binding of syndecan-1 to laminin-5 α3 chain LG4-5 domain.
Target
LAMA3
Target Alias Names
E170, LOCS, BM600, LAMNA
Isotypes/Mimetics
Chimeric (mouse/human) IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression