Description
Recombinant Human Antibody (Fab19) is capable of binding to Kit, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-Kit mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-Kit mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
KIT
Target Alias Names
KIT, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, PBT, SCFR, C-Kit, CD117, mast/stem cell growth factor receptor Kit, p145 c-kit, proto-oncogene c-Kit, piebald trait protein, soluble KIT variant 1, tyrosine-protein kinase Kit, proto-oncogene tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression