Description
This product is a recombinant human antibody that binds to human KDR expressed on the surface of a cell and inhibits KDR signaling activity in the cell. The affinity measurement, EC50 measurement, and IC50 measurement of this antibody are 1.08 nM, 0.5 nM, and 25.3 nM, respectively.
Target
KDR
Target Alias Names
Kinase Insert Domain Receptor, Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase), Vascular Endothelial Growth Factor Receptor 2, Protein-Tyrosine Kinase Receptor Flk-1, Fetal Liver Kinase 1, EC 2.7.10.1, VEGFR2, FLK1, Tyrosine Kinase Growth Factor Receptor
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression