Description
Recombinant Human Antibody (b70) is capable of binding to Protein jagged-1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-Protein jagged-1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-Protein jagged-1 mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
JAG1
Target Alias Names
JAG1, jagged 1, AGS, AHD, AWS, HJ1, CD339, JAGL1, protein jagged-1
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression