Description
Recombinant Human Antibody (6RL9) is capable of binding to IL-6R, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IL-6R mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IL-6R mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
IL6R
Target Alias Names
IL6R, interleukin 6 receptor, IL6Q, gp80, CD126, IL6RA, IL6RQ, IL-6RA, IL-6R-1, interleukin-6 receptor subunit alpha, IL-6R 1, CD126 antigen, membrane glycoprotein 80, IL-6 receptor subunit alpha
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression