Description
IL-17A is T-cell-derived cytokine, which has a pleiotropic pro-inflammatory activity. In vitro, IL-17A regulate fibroblasts and synovial cells produce inflammatory mediators, synergies with other pro-inflammatory cytokines and promote cartilage degradation and bone resorption of osteoclasts.
Target
IL17A
Target Alias Names
IL17A, interleukin 17A, IL17, CTLA8, IL-17, IL-17A, interleukin-17A, CTLA-8, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression