Description
The monoclonal antibody antigen is a transmembrane glycoprotein expressed in normal colonic and bowel epithelium and human colon cancers. A humanized version of mAb may be characterized to identify epitopes relating to the observed immune response in humans as a therapeutic antibody.
Target
HLA-DRB1
Target Alias Names
HLA-DRB1, major histocompatibility complex, class II, DR beta 1, SS1, DRB1, HLA-DRB, HLA-DR1B
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression