Description
This product is a recombinant human antibody that recognizes GLP1R. 3F52 specifically binds to human and cynomolgus monkey GLP-1R. 3F52 blocked the GLP-1 binding site of the ECD directly and thereby acts as a competitive antagonist of native GLP-1. mAb 3F52 functioned as a neutral antagonist.
Target
GLP1R
Target Alias Names
Glucagon Like Peptide 1 Receptor, Glucagon-Like Peptide 1 Receptor, GLP-1 Receptor, GLP-1-R, GLP-1R, Seven Transmembrane Helix Receptor, GLP1 Receptor, GLP-1
Isotypes/Mimetics
Chimeric (mouse/human) IgG4, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression