Description
This product is a recombinant Human antibody that can recognize Connexin26. The antibody binds an extracellular epitope of Cx26. abEC1.1 inhibits connexin hemichannels by binding an epitope at the apex of the EC1 loop.
Target
GJB2
Target Alias Names
Connexin 26, Cx26, HID, KID, PPK, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A
Isotype/Mimetic
Human IgG1
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression