Description
Provided is a specific monoclonal antibody against the ED-B domain of Fibronectin, a maker of angiogenesis. ME4C binds to the ED-B domain with a dissociation constant in the nanomolar range and specifically stains tumors blood vessels of human and murine origin.
Target
FN1
Target Alias Names
FN, CIG, FNZ, MSF, ED-B, FINC, GFND, LETS, GFND2, SMDCF
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression