Description
Antibody ESC14 is a fully human, mouse/human cross-reactive, high affinity anti-FAP antibody that induces relevant regulatory activities on target cells pointing out to their therapeutic impact.
Target
FAP
Target Alias Names
FAP, fibroblast activation protein, alpha, FAPA, SIMP, DPPIV, prolyl endopeptidase FAP, seprase, FAPalpha, dipeptidyl peptidase FAP, surface-expressed protease, post-proline cleaving enzyme, gelatine degradation protease FAP, integral membrane serine protease, serine integral membrane protease, 170 kDa melanoma membrane-bound gelatinase
Isotype/Mimetic
Human IgG1
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression