Description
Recombinant Human Antibody (10H10) is capable of binding to F3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-F3 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-F3 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
F3
Target Alias Names
F3, coagulation factor III (thromboplastin, tissue factor), TF, TFA, CD142, tissue factor
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression