Description
The mAb is a recombinant human antibody that binds to HER-3. The antibody has a discontinuous epitope located in the minor ligand-binding domain. The Kd value is 1 nM determined by FACS. The antibody can be used for Breast cancer study.
Target
ERBB3
Target Alias Names
Erb-B2 Receptor Tyrosine Kinase 3, V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3, Tyrosine Kinase-Type Cell Surface Receptor HER3, Human Epidermal Growth Factor Receptor 3, Proto-Oncogene-Like Protein C-ErbB-3, EC 2.7.10.1, HER3, Lethal Congenital Contracture Syndrome 2, Receptor Tyrosine-Protein Kinase ErbB-3, P180-ErbB3
Isotype/Mimetic
Human IgG1
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression