Description
Recombinant Human Antibody (1C1) is capable of binding to EphA2, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-EphA2 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-EphA2 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
EPHA2
Target Alias Names
EPHA2, EPH receptor A2, ECK, CTPA, ARCC2, CTPP1, CTRCT6, ephrin type-A receptor 2, soluble EPHA2 variant 1, tyrosine-protein kinase receptor ECK, epithelial cell receptor protein tyrosine kinase
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression