Description
An antibody EGL2 specifically binds to epidermal growth factor receptor (EGFR) in cancer cells. It was confirmed that anti-EGFR antibody EGL2 can inhibit tyrosine phosphorylation that is one of the signal transductions that occur in actual cells. The antibody can be used in some immunoassay techniques such as: ELISA, flow cytometry, Immunofluorescence and Inhibition.
Target
EGFR
Target Alias Names
Epidermal Growth Factor Receptor, Receptor Tyrosine-Protein Kinase ErbB-1, Erb-B2 Receptor Tyrosine Kinase 1, Proto-Oncogene C-ErbB-1, EC 2.7.10.1, ERBB1, ERBB, HER1, Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog), Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian)
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression