Description
This product is a humanized IgG1 kappa antibody targeting human epidermal growth factor receptor, derived from a mouse antibody m225. This antibody has lower immunogenicity and higher target binding activity, so the antibody has stronger biological activity and in-vitro and in-vivo antineoplastic activity, and it is expected that the antibody has a smaller side-effect and a better curative effect in clinic application.
Target
EGFR
Target Alias Names
EGFR, Erb-B2 Receptor Tyrosine Kinase 1, Epidermal Growth Factor Receptor, MENA, Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog), Receptor Tyrosine-Protein Kinase ErbB-1, ERBB, ERBB1
Isotypes/Mimetics
Humanized IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression