Description
This is a human pemphigus vulgaris monoclonal autoantibodies isolated by phage display. The clone (D31)2/28 can interfere with adhesion mediated by both human Dsg3 and human Dsg1. While it recognized only mDsg1 and not mDsg3.
Target
DSG1
Target Alias Names
Desmoglein 1, Pemphigus Foliaceus Antigen, Desmosomal Glycoprotein 1, Cadherin Family Member 4, CDHF4, DG1, EPKHIA, EPKHE, PPKS1, SPPK1, DSG, DGI
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression