Description
This product is a recombinant human antibody that specifically targets C-X-C motif chemokine ligand 12 with the highest affinity, boasting a KD value of 1 nM. It has been shown to effectively inhibit CXCL12 induced migration of ovarian cancer cells as demonstrated by a transwell migration assay.
Target
C-X-C motif chemokine ligand 12
Target Alias Names
C-X-C Motif Chemokine Ligand 12, Pre-B Cell Growth-Stimulating Factor, Chemokine (C-X-C Motif) Ligand 12, Intercrine Reduced In Hepatomas, Stromal Cell-Derived Factor 1, SDF1, PBSF, IRH, C-X-C Motif Chemokine 12
Isotype/Mimetic
Chimeric (Mouse/Human) IgG2a
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression