Description
This product is a recombinant human antibody that is designed to target CTLA4. Through competitive inhibition assay, the antibody effectively disrupts the interaction between hCD80 and hCD86 (1 μg/mL) with hCTLA-4 at a concentration exceeding 1 μg/mL.
Target
CTLA4
Target Alias Names
Cytotoxic T-Lymphocyte Associated Protein 4, Insulin-Dependent Diabetes Mellitus 12, Celiac Disease 3, CTLA-4, CD152, Ligand And Transmembrane Spliced Cytotoxic T Lymphocyte Associated Antigen 4, Cytotoxic T Lymphocyte Associated Antigen 4 Short Spliced Form, Cytotoxic T-Lymphocyte-Associated Serine Esterase-4, Cytotoxic T-Lymphocyte-Associated Antigen 4, Cytotoxic T-Lymphocyte Protein 4
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression