Description
This product is a recombinant human IgG2 antibody that was designed to target CSF1R. It has demonstrated the capacity to effectively inhibit ligand-induced pTyr/c-fms in the 293T3/c-fms assay system, showcasing consistent inhibition at a concentration of 1 μg/mL (83 nM).
Target
CSF1R
Target Alias Names
Colony Stimulating Factor 1 Receptor, McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog, Proto-Oncogene C-Fms, CSF-1 Receptor, CD115 Antigen, EC 2.7.10.1, M-CSF-R, CSF-1R, FMS, Macrophage Colony Stimulating Factor I Receptor
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression