Description
The CFH inhibitor is a CFH specific antibody. More particularly, the CFH inhibitor is a CFH specific monoclonal antibody. The CFH inhibitor stops combination of CFH and C3b to improve deposition of C3b on tumor cells and promote compliment mediated cytotoxic effect.
Target
CFH
Target Alias Names
Complement Factor H, Age-Related Maculopathy Susceptibility 1, H Factor 2 (Complement), H Factor 1 (Complement), Beta-1H, HF1, HF2, HF, Adrenomedullin Binding Protein, Beta-1-H-Globulin, Factor H-Like 1
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression