Description
The product is a recombinant human antibody targets for CD40. It binds to human Cd40-Fc using Surface Plasmon Resonance, with an affinity of 0.271 nM. HPAB-0139CQ effectively attaches to the cell surface of B cells and DCs present in lymphoid organs.
Target
CD40
Target Alias Names
CD40 Molecule, CD40 Molecule, TNF Receptor Superfamily Member 5, CD40L Receptor, TNFRSF5, CDW40, Bp50, Tumor Necrosis Factor Receptor Superfamily, Member 5
Isotypes/Mimetics
Human IgG4, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression